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Top : Colorectal > Colorectal Oncogene

Colorectal Oncogene
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1. : The AMEDEO Literature Guide

Amedeo offers weekly literature overviews in scientific medicine. Select a topicdefine your favourite journalsand you'll receive the weekly AMEDEO literature newsletters. Downregulation of EphA7 by hypermethylation in colorectal cancer. Oncogene 2005;. and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer. Oncogene 2005;.
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http://www.amedeo.com/medicine/crn/onco.htm
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2. A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers -- Bischoff et al. 17

This Article. Services. PubMed. The EMBO Journal Vol. 17 pp. 3052-30651998. A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers. James R. of colorectal malignancies colorectal cancers. Furthermoreoverexpression of aurora2 transforms rodent fibroblasts. These observations implicate aurora2 as a potential oncogene
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http://embojournal.npgjournals.com/cgi/content/full/17/11/3052
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3. AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis -- Roy et al. 23 (1): 201

critical event in the development of colorectal malignanciesalthough the mechanism(s) remain that the AKT proto-oncogene is overexpressed in colorectal cancer. The upregulation
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http://carcin.oxfordjournals.org/cgi/content/full/23/1/201
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4. American Society for Gastrointestinal Endoscopy :: Member Site

Commentary. Colorectal cancer is the second most common cancer for men and women proliferationwhich is followed by oncogene activation and chromosomal deletionswhich lead
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http://www.asge.org/nspages/practice/patientcare/93-colorectal.cfm
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5. Analysis of Human DNA in Stool Samples

In patients with known colorectal cancerdetection of MSI in tumor tissue has been used as a triage K-Ras is an oncogene whose activity may be increased by mutations; TP
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http://www.regence.com/trgmedpol/lab/lab37.html
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6. Biocompare News - Important Discovery About Second Most Fatal Cancer

Colorectal cancer is the second most frequent cause of death due to cancer (after lung cancer) in Canada These polyps also show mutation of the oncogene BRAF and DNA methylation
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http://news.biocompare.com/newsstory.asp?id=70246
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7. c-Ki-ras mutations in colorectal adenocarcinomas from a country with a rapidly changing colorectal cancer incidence

British Journal of Cancer (BJC) provides a forum for communicating the very best cancer research to a broad audience. BJC works with a distinguished team of international experts to ensure the highest standards of selection and review. the c-Ki-ras proto-oncogene in colorectal adenocarcinomas from two different
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http://www.nature.com/cgi-taf/dynapage.taf?file=/bjc/journal/v81/n2/abs/6690683a.html
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8. Cancer Spectrum: CANCERLIT® Citation

Sign In to JNCI Cancer Spectrum. Quick Search in 84 patients with recurrent or metastatic colorectal cancer submitted to a chemotherapy regimen including Protein p53. Proto-Oncogene Proteins. Proto-Oncogene Proteins c-bcl-2
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http://jncicancerspectrum.oxfordjournals.org/cgi/cancerlit/11237386
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9. Cancer Spectrum: Kopreski et al.pp. 918-923.

Sign In to JNCI Cancer Spectrum. Quick Search patients undergoing colonoscopy. Colorectal biopsies were performed as clinically indicated in identifying K-ras oncogene mutations in preneoplastic colorectal lesions. Cancer
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http://jncicancerspectrum.oxfordjournals.org/cgi/content/full/jnci;92/11/918
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10. CK2 protein sustains colon cancer cells by sabotaging ability to commit suicide

a deadly role in colorectal carcinoma by blocking the colorectal cancer to investigate the role of CK2 in tumors is now bearing fruit " said Houghtonsenior author of the Oncogene
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http://www.medicalnewstoday.com/medicalnews.php?newsid=20332&nfid=rssfeeds
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11. CK2 protein sustains colon cancer cells by sabotaging ability to commit suicide

a deadly role in colorectal carcinoma by blocking the colorectal cancer to investigate the role of CK2 in tumors is now bearing fruit " said Houghtonsenior author of the Oncogene
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http://www.eurekalert.org/pub_releases/2005-02/sjcr-cps022305.php
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12. col1 col2 col3 col4 col5 col6 col7 1 "Bakers.j.fearone.r.nigroj.m.

denaturing gradient gel electrophoresis in colorectal tumors "Oncogene: 82213-2220 (1993)" Database p53 mutations in primary colorectal tumors "Oncogene: 62121-2128 (1991)" p53
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http://www.infobiogen.fr/services/LISTS/DB/p53/refr3.txt
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13. Colorectal Cancer

Cancers of the colon and rectum (designated as colorectal cancers or CRCs) are the third most common activating mutations of the K-ras oncogene are two of the earliest changes
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http://www.oncodx.com/cancers/colorectal.htm
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14. Colorectal Cancer Prevention

Colorectal Cancer Prevention. Prevention. CASE 7. A 42-year-old Caucasian male comes into your clinic for a follow up visit for his blood pressure which you have been monitoring. For examplethe K-ras oncogene product is altered in many colorectal cancers and researchers are testing ways to help
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http://www.catchum.utmb.edu/FinalProject/pgeneral.html
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15. COX-2 Inhibitors and Cancer Chemoprevention

September 172005. COX-2 and Colorectal Cancer. The Scope of the Problem. Dr. Colorectal cancer evolves through a multistep process in which some genes are activatedsuch as the oncogene Ras as 80% of sporadic colorectal tumors. HNPCC syndromes
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http://www.medscape.com/viewarticle/412929_2
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16. Department of Pharmacology & Molecular Sciences

Our efforts are largely focused on colorectal cancer which is the second leading cause of cancer genetic changes affecting at least one oncogene and several tumor suppressor genes
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http://www.hopkinsmedicine.org/pharmacology/pages/faculty/kinzler.html
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17. DNA Alkylation and Repair in the Large Bowel: Animal and Human Studies -- Povey et al. 132 (11): 3518 -- Journal of

has been detected in human colorectal DNA at levels comparable to in the K-ras oncogene result from the formation and persistence of O6-alkylguanine lesions in colorectal DNA. Human
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http://www.nutrition.org/cgi/content/full/132/11/3518S
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18. Epidermal growth factor receptor signaling in colorectal cancer: preclinical data and therapeutic perspectives --

which comprises four proteins encoded by the c-erbB proto-oncogene. EGFR is known to activate a during apoptosis in human colorectal cancer cells. Oncogene 1998; 17: 9991007
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http://annonc.oxfordjournals.org/cgi/content/full/16/2/189
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19. Expression of c-Met and Heparan-Sulfate Proteoglycan Forms of CD44 in Colorectal Cancer -- Wielenga et al. 157 (5):

Leppert MNakamura YWhite RSmits AMMBos JL: Genetic alterations during colorectal-tumor development 2 in primary human colorectal carcinomas. Oncogene 19927:181-185[Medline
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http://ajp.amjpathol.org/cgi/content/full/157/5/1563
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20. Frequent loss of SMAD4/DPC4 protein in colorectal cancers -- Salovaara et al. 51 (1): 56 -- Gut

Author. Keyword(s) Vol
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http://gut.bmjjournals.com/cgi/content/full/51/1/56
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21. Frequent loss of SMAD4/DPC4 protein in colorectal cancers -- Salovaara et al. 55 (6): 385 -- Molecular Pathology

Author. Keyword(s) Vol
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http://mp.bmjjournals.com/cgi/content/full/55/6/385
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22. Gene Found In 50% Of Colon Tumors

gene called aurora2 can be found in more than half of colorectal cancers testedaccording to a report identified two versions of an oncogene (a gene that can be linked
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http://www.personalmd.com/news/a1998060806.shtml
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23. GENERATIONS - Publications

The Hong Kong Colorectal Cancer Registry has published many articles and abstracts and provides a list here for reference. underlying mismatch repair deficiency in colorectal and HNPCC-related cancers. Oncogene 2002 Oct 24; 21(49 BRAF and KRAS Mutations in Colorectal Neoplasia. Cancer Res 2002 Nov15
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http://www.generations.hk.com/background/Publications.php3
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24. GENERATIONS - Registry Information Page

An overview of Colorectal Cancer and the role of the Hong Kong Registry in helping those people and their families affected by colon cancer. In Hong Kongcolorectal cancer has increased rapidly in recent decades to become the second commonest repair deficiency in colorectal and HNPCC-related cancers. Oncogene 2002;21(49
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http://www.generations.hk.com/background/Info_Registry.php3
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25. Genomics|HuGENet|Reviews|Folate Metabolism and Colorectal Neoplasia

evidence suggests that folate is involved in colorectal neoplasia. Some polymorphic genes involved in causing DNA hypomethylation and proto-oncogene activation and/or 2) by inducing
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http://www.cdc.gov/genomics/hugenet/reviews/neoplasia.htm
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26. Genomics|HuGENet|Reviews|hMLH1 and hMSH2 and Colorectal Cancer

International Collaborative Group on Hereditary Nonpolyposis Colorectal Cancer. ICG-HNPCC mutation database role of hMSH2 in sporadic colorectal cancer. Oncogene 1996;12:26419
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http://www.cdc.gov/genomics/hugenet/reviews/mismatch.htm
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27. Hereditary Ovarian Cancer - May 2001: 705709

coding regions in lungbreastovarian and colorectal cancers. SO - Oncogene 2001 Feb 22;20(8):1005-9 region 6q. 27. SO - Oncogene 2001 Feb 22;20(8):980
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http://www.acor.org/cnet/705709.html
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28. HRAS - v-Ha-ras Harvey rat sarcoma viral oncogene homolog - Cancer GeneticsWeb

HRAS Mutations in Colorectal Cancer. - HRAS Minisatellite Alleles and Colorectal Cancer Risk Overview: HRAS (sometimes just reffered to as Ras) is an oncogene found on chromosome 11
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http://www.cancerindex.org/geneweb/HRAS.htm
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29. HUMAN CHROMOSOME #8

CRC1. colorectal carcinoma tumor suppressor gene 1 Moloney murine sarcoma viral (v-mos) oncogene homolog
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http://www.il-st-acad-sci.org/genecats/hsa08.html
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30. Human Genetics - Faculty Profiles

Our efforts are largely focused on colorectal cancerwhich is the second leading cause of cancer genetic changes affecting at least one oncogene and several tumor suppressor genes
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http://www.hopkinsmedicine.org/humangenetics/facultypages/kinzler.html
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